Vontobel Stiftung has awarded Dr. Sheida Moghadamrad for her project, which aims to deepen our understanding of Metabolic dysfunction fatty liver disease (MASLD) by exploring the role of Paneth cells -specialized intestinal innate immune cells- in regulating gut barrier function and lipid absorption. Utilizing advanced methodologies such as in vivo laser endomicroscopy, 3D and 2D…
DetailsCongratulations to Elisa Sorrenti, PhD student at #LRT_EOC in Prof. Giandomenica Iezzi’s lab.for the best oral presentation at the BioMed PhD Day 2024 entitled “Interplay between tumor-associated neutrophils and gut microbiota in human colorectal cancer”.
The Swiss National Science Foundation has awarded a prestigious research grant to Prof. Lucio Barile from the Istituto Cardiocentro Ticino and Laboratories for Translational Research of Ente Ospedaliero Cantonale, for an ambitious bilateral research project in collaboration with a research group led by Dr. Marzia De Bortoli at Eurac Research Institute in Bolzano. The project…
DetailsIt is our great pleasure to announce that Prof. Bersini was granted 800’000 chf funding to continue his research on vascular aging. The funded project deals with the “biofabrication” of microscale models of the blood brain barrier through miniaturized systems called “organ-on-a-chip”. Using human vascular cells, the project will allow to build 3D models of…
DetailsIntervista a Paolo Paganetti (Laboratori EOC). È sua la scoperta che la proteina Tau, protagonista dell’Alzheimer, regola anche l’efficacia di un’altra proteina (la p53) fondamentale nello sviluppo del cancro https://www.ticinoscienza.ch/it/news.php?quegli-intrecci-misteriosi-fra-origine-dell-alzheimer-e-quella-dei-tumori
DetailsConducting laboratory research with the primary objective of identifying practical applications to improve patient care (this is what translational research is). Taking full advantage of synergies within the EOC’s facilities, also thanks to its group leaders, who balance their work between research laboratories and patient care in hospital. Aiming to use innovative and cutting-edge techniques,…
DetailsA new study of the nephrology group combined functional imaging with single cell sequencing to delineate the landscape of responses to proteinuria along the entire nephron. The study highlights that proteinuria induces both remodeling and injury, in a segment specific manner. This research is a collaboration with Sophie de Seigneux’s lab in Geneva and Andrew…
DetailsThe work carried out by the lab of Nephrology, in collaboration with the University of Paris, shows that decreased urinary taurine concentrations are a hallmark of acutely and chronically injured kidney allografts and are predictive of graft loss. The study is published in Transplantation, https://pubmed.ncbi.nlm.nih.gov/38502560/
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DetailsA transfer learning approach to exploit the power of single-cell technologies toward clinical applications has been developed by the nephrology group in collaboration with Dalle Molle Institute for Artificial Intelligence and the University Hospital of Geneva. The work has been published in iScience. https://doi.org/10.1016/j.isci.2024.109271
The nephrology group identified the critical role of SOX9 switch in kidney regeneration and fibrosis. The studies, performed in collaboration with the group of Prof. Sanjeev Kumar (Los Angeles), were recently published in Science. https://www.science.org/doi/10.1126/science.add6371
